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Smokers are more likely to be opioid abusers than non-smokers.

Source: Zale EL, Dorfman ML, Hooten WM, Warner DO, Zvolensky MJ, Ditre JW. Tobacco Smoking, Nicotine Dependence, and Patterns of Prescription Opioid Misuse: Results From a Nationally Representative Sample. Nicotine Tob Res. 2014;17(9):1096-103.
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In 2016, 1 in 5 deaths among young adults were opioid related.

Source: Gomes T, Tadrous M, Mamdani MM, Paterson J, Juurlink DN. The burden of opioid-related mortality in the united states. JAMA Network Open. 2018;1(2):e180217.
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The average days’ supply of opioids prescribed by doctors in the U.S. increased 33% from 2006 to 2015.

Source: Guy GP Jr., Zhang K, Bohm MK, et al. Vital Signs: Changes in Opioid Prescribing in the United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:697–704. DOI: http://dx.doi.org/10.15585/mmwr.mm6626a4
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80% of heroin users started with a prescription painkiller.

Source: Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend (2013) 132:95–100
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In 2010, for every woman that died of a prescription painkiller overdose, 30 went to the ER for misuse or abuse.

Source: Centers for Disease Control and Prevention. Vital Signs: Overdoses of Prescription Opioid Pain Relievers and Other Drugs Among Women — United States, 1999–2010. MMWR 2013;62:537-542.
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In 2013, the United States, which continued to be the principal consumer country of oxycodone, accounted for 78 percent of the world total.

Source: United Nations: International Narcotics Control Board. Report of the International Narcotics Control Board for 2014. Accessed June 2018.
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Every day in 2017, an estimated 1,300 young adults misused an opioid prescription for the first time.

Source: Substance Abuse and Mental Health Services Administration. (2018). Key substance use and mental health indicators in the United States: Results from the 2017 National Survey on Drug Use and Health (HHS Publication No. SMA 18-5068, NSDUH Series H-53). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration.
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Taking opioids after wisdom teeth removal increases the odds of long term use.

Source: Harbaugh CM, Nalliah RP, Hu HM, Englesbe MJ, Waljee JF, Brummett CM. Persistent Opioid Use After Wisdom Tooth Extraction. JAMA. 2018;320(5):504–506. doi:10.1001/jama.2018.9023
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More than 17,000 people died from prescription opioid overdoses in 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1
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Since 1999, over 9,000 children and teens have died from opioid overdoses.

Source: Centers for Disease Control and Prevention. CDC WONDER: Multiple Cause of Death 1999-2017.
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More than two-thirds of people admitted into substance abuse treatment programs first used a non-heroin opioid by age 25.

Source: Substance Abuse and Mental Health Services Administration, Center for Behavioral Health Statistics and Quality. Treatment Episode Data Set (TEDS): 2003-2013. National Admissions to Substance Abuse Treatment Services. Rockville, MD: Substance Abuse and Mental Health Services Administration, 2015.
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Every day, 130 Americans die after overdosing on opioids.

Source: Hedegaard H, Miniño AM, Warner M. Drug overdose deaths in the United States, 1999–2017. NCHS Data Brief, no 329. Hyattsville, MD: National Center for Health Statistics. 2018.
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