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80% of heroin users started with a prescription painkiller.

Source: Jones CM. Heroin use and heroin use risk behaviors among nonmedical users of prescription opioid pain relievers – United States, 2002-2004 and 2008-2010. Drug Alcohol Depend (2013) 132:95–100
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In 2016, 1 in 5 deaths among young adults were opioid related.

Source: Gomes T, Tadrous M, Mamdani MM, Paterson J, Juurlink DN. The burden of opioid-related mortality in the united states. JAMA Network Open. 2018;1(2):e180217.
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As the death rate of major killers like cancer and heart disease decline, opioid death rates continue to rise.

Source: National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64. Hyattsville, MD. 2015. https://www.cdc.gov/nchs/data/hus/hus14.pdf. Accessed June 2018.
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Every day in 2017, an estimated 1,300 young adults misused an opioid prescription for the first time.

Source: Substance Abuse and Mental Health Services Administration. (2018). Key substance use and mental health indicators in the United States: Results from the 2017 National Survey on Drug Use and Health (HHS Publication No. SMA 18-5068, NSDUH Series H-53). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration.
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Over half of young adults who misused prescription opioids got them from a friend or family member.

Source: Center for Behavioral Health Statistics and Quality. (2017). 2016 National Survey on Drug Use and Health: Detailed Tables. Substance Abuse and Mental Health Services Administration, Rockville, MD.
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More than 17,000 people died from prescription opioid overdoses in 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1
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Dependence on prescription opioids can happen after just five days.

Source: Shah A, Hayes CJ, Martin BC. Characteristics of Initial Prescription Episodes and Likelihood of Long-Term Opioid Use — United States, 2006–2015. MMWR Morb Mortal Wkly Rep 2017;66:265–269. DOI: http://dx.doi.org/10.15585/mmwr.mm6610a1
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In a grim milestone, more people died from heroin-related causes than from gun homicides in 2016.

Source: Centers for Disease Control and Prevention, National Center for Health Statistics. Multiple Cause of Death, 1999-2016 on CDC WONDER Online Database, released 2017.
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In 2011, more than 420,000 emergency department visits were related to the misuse or abuse of narcotic pain relievers.

Source: Substance Abuse and Mental Health Services Administration, Drug Abuse Warning Network, 2011: National Estimates of Drug-Related Emergency Department Visits. Rockville, MD: Substance Abuse and Mental Health Services Administration; 2013.
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In 2015 , the opioid epidemic cost the US more than $500 billion dollars.

Source: The Council of Economic Advisers. The Underestimated Cost of the Opioid Crisis. Washington, DC: Executive Office of the President; 2017.
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In 2017, two out of three drug overdose deaths involved some type of opioid.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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Heroin-related overdose deaths increased 5x from 2010 to 2017.

Source: Scholl L, Seth P, Kariisa M, Wilson N, Baldwin G. Drug and Opioid-Involved Overdose Deaths — United States, 2013–2017. MMWR Morb Mortal Wkly Rep 2019;67:1419–1427. DOI: http://dx.doi.org/10.15585/mmwr.mm675152e1.
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